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RESOURCES & SUPPORT

You aren’t on this journey alone. Access resources and support that can help you take an active role in your care and get the most from your treatment.

SPEVIGO® (spesolimab-sbzo) injection is a prescription medicine used to treat generalized pustular psoriasis (GPP) in adults and children 12 years of age and older who weigh at least 88 pounds (40 kg). It is not known if SPEVIGO is safe and effective in children under 12 years of age or who weigh less than 88 pounds (40 kg). 

Doctor And Patient Consultation About GPP

TAKING AN ACTIVE ROLE

When it comes to taking on GPP, the more informed you are, the better. Use these tips and tools to learn ways to cope with GPP and work with your dermatologist to find a treatment strategy that works for you.

STARTING SPEVIGO

Knowing what to expect when starting a new treatment can make all the difference. Access tools and resources for people prescribed SPEVIGO all in one spot.

IV Infusion Resources 

The Infusion Experience (PDF)

Prepare for Your Appointment (Video)

Music Playlist Curated for Infusion Therapy (Playlist)

SC Injection Resources 

Step-By-Step SC Injection Guide (Video)
Step-By-Step Instructions (PDF)

Self-Injection Placemat (PDF)

General SPEVIGO Patient 
Resources

Meet Your Personal Care Team (PDF)

Patient ID Card (PDF)

SUPPORT AT EVERY STEP

It’s normal to have questions about starting a new treatment. Let us help you find answers. The BI SOLUTIONS PLUS program is a complimentary patient support program dedicated to people prescribed SPEVIGO. It pairs your individual journey with a range of services and support, including a dedicated Patient Navigator, a Patient and Community Clinical Educator, financial assistance options, and supplemental services designed to make your SPEVIGO experience as seamless as possible.

Click here to enroll or call 833-SPEVIGO (773-8446), Monday-Friday, (8AM-8PM ET), to learn more about the program.

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  • Your dermatologist’s office can enroll you in the BI SOLUTIONS PLUS program. You can also enroll online.

  • Within 24 hours of enrollment, you will receive a welcome call from your dedicated Patient Navigator.

  • Your dedicated Patient Navigator is available to support you throughout your treatment journey with SPEVIGO. They are available to answer questions about GPP; help you understand your insurance coverage, as well as any out-of-pocket costs; and help coordinate your treatment with SPEVIGO every step of the way.

  • If you choose, your Patient Navigator can also connect you with a Patient and Community Clinical Educator. 

    • Patient and Community Clinical Educators are not doctors and cannot provide medical treatment or advice.
    • Patient and Community Clinical Educators can provide information and resources on your condition, what to expect with SPEVIGO, and supplemental injection education.
    • Each session is personalized, based on your needs, and can take place in person or over the phone.

Please note: If you have specific questions or concerns about your treatment, please speak to your healthcare provider.

 

  • Your Patient Navigator can help you understand your insurance coverage for SPEVIGO, as well as any anticipated out-of-pocket costs.

  • They will also provide information about the SPEVIGO Copay Program* and any other BI SOLUTIONS PLUS financial assistance options available for eligible commercially insured patients. They may be able to provide information about other financial options as well.

*Eligibility and enrollment required. For use only with commercial prescription insurance. Valid for U.S. patients, ages 12 years and older. Must be used for an FDA-approved indication. Additional terms and conditions apply. 

If your GPP flare is being treated with an infusion:

  • Your Patient Navigator can help coordinate finding an infusion center where you can receive treatment.

  • They will also contact you before your appointment to confirm time and location and discuss any questions you might have.

If you were prescribed subcutaneous injections: 

  • Your Patient Navigator will work with you, the Specialty Pharmacy, and your healthcare provider to coordinate your initial dose.

  • Your Patient and Community Clinical Educator can meet with you in person to help you understand SPEVIGO and help familiarize you with the steps detailed in the Instructions for Use. 

  • At your request, they can also provide an injection demonstration kit that you can use for practice, a sharps container for disposing of your syringes, and a travel case to help keep your SPEVIGO cold.

  • Based on your preferences, your Patient Navigator will continue to follow up with you. They are available to answer your questions, offer support, and provide injection reminders and tips throughout your treatment journey. Your Patient Navigator can contact you by phone, email, or text—whatever you prefer.

  • Use the tools and resources provided by your Patient Navigator and this website to help you take an active role in your care and get the most from your treatment plan.

ENROLL IN BI SOLUTIONS PLUS

If you have been prescribed SPEVIGO to treat your GPP, take advantage of the BI SOLUTIONS PLUS program. BI SOLUTIONS PLUS is a patient support program designed with your needs in mind.  
 
Enroll Now

SAVE ON SPEVIGO

When considering your treatment options, cost can be an important factor. Find out if you are eligible for the SPEVIGO Copay Program.†

A drawn cartoon of a female patient using a laptop

ELIGIBLE ENROLLED† PATIENTS WITH COMMERCIAL INSURANCE MAY PAY AS LITTLE AS $0 PER TREATMENT

Through the SPEVIGO Copay Program, you may be able to pay as little as $0 per treatment. Sign up to get started. Eligible patients will receive their SPEVIGO Copay card by email. Terms and conditions apply.

For questions about the SPEVIGO Copay Program or to learn more about other potential ways to save, contact BI SOLUTIONS PLUS at 833-SPEVIGO (773-8446), Monday-Friday, (8AM-8PM ET).

†Eligibility and enrollment required. For use only with commercial prescription insurance. Valid for U.S. patients, ages 12 years and older. Must be used for an FDA-approved indication. Additional terms and conditions apply.

STAY INFORMED WITH SPEVIGO

Sign up to receive updates and information about SPEVIGO. Get GPP resources designed to help you move forward and take control of your care.

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What is SPEVIGO?

SPEVIGO is a prescription medicine used to treat generalized pustular psoriasis (GPP) in adults and children 12 years of age and older who weigh at least 88 pounds (40 kg). It is not known if SPEVIGO is safe and effective in children under 12 years of age or who weigh less than 88 pounds (40 kg). 

Important Safety Information

Do not receive SPEVIGO if you or your child have had a severe or life-threatening allergic reaction to spesolimab-sbzo or any of the ingredients in SPEVIGO.  

What is the most important information I should know about SPEVIGO?

SPEVIGO may cause serious side effects, including:

  • Infections. SPEVIGO may lower the ability of your or your child’s immune system to fight infections and may increase your or your child’s risk of infections. Your healthcare provider should check you or your child for infections and tuberculosis (TB) before starting treatment with SPEVIGO and may treat you or your child for TB before you begin treatment with SPEVIGO if you have a history of TB or have active TB. Your healthcare provider should watch you or your child closely for signs and symptoms of TB during or after treatment with SPEVIGO. Tell your healthcare provider right away if you or your child have an infection or have symptoms of an infection during or after treatment with SPEVIGO, including:
    • fevers, chills, or sweats
    • muscle aches
    • cough
    • shortness of breath
    • blood in your phlegm (mucus)
    • burning when you urinate
    • urinating more often than normal
  • Allergic reactions and infusion-related reactions. Serious allergic reactions may happen during or after your or your child’s SPEVIGO injection. If you or your child have a serious allergic reaction, your healthcare provider will stop treatment with SPEVIGO. If you or your child are given SPEVIGO in a vein (intravenously) and have an infusion-related reaction, your healthcare provider will stop your or your child’s SPEVIGO infusion and treat your or your child’s symptoms and may restart SPEVIGO at a slower infusion rate. Tell your healthcare provider or get emergency medical help right away if you or your child get any of the following symptoms during or after your or your child’s SPEVIGO injection: 
    • feeling faint, dizzy, or lightheaded
    • swelling of your face, eyelids, lips, mouth, tongue, or throat
    • trouble breathing or throat tightness
    • fever
    • mouth sores
    • chest tightness
    • hives or skin rash that is different than the rash from generalized pustular psoriasis (GPP)
    • itching
    • swollen lymph nodes
Before you or your child receive SPEVIGO, tell your healthcare provider about all of your medical conditions, including if you or your child: 
  • have an infection that does not go away or that keeps coming back.
  • have TB or have been in close contact with someone with TB.
  • have recently received or are scheduled to receive an immunization (vaccine). You or your child should not receive live vaccines during and for at least 16 weeks after treatment with SPEVIGO. You or your child should be brought up to date with all vaccines before starting SPEVIGO.
  • are pregnant or plan to become pregnant. It is not known if SPEVIGO can harm your or your child’s unborn baby. 
  • are breastfeeding or plan to breastfeed. It is not known if SPEVIGO passes into your breast milk. Talk to your healthcare provider about the best way to feed your or your child’s baby during treatment with SPEVIGO. 

Tell your healthcare provider about all the medicines you or your child take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. 

What are the possible side effects of SPEVIGO?

The most common side effects of SPEVIGO given in a vein (intravenously) for GPP flare treatment include: 

  • feeling tired or weak
  • nausea and vomiting
  • headache
  • itching or itchy bumps
  • a collection of blood under the skin at the infusion site or bruising
  • urinary tract infection

The most common side effects of SPEVIGO when given under the skin (subcutaneously) for treatment of GPP when not experiencing a flare include:  

  • redness, pain, swelling, hardening, hives, or warmth at the injection site 
  • joint pain  
  • urinary tract infection 
  • itching

These are not all of the possible side effects of SPEVIGO. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

CL-SPG-100004 03.18.2024

SPEVIGO is a registered trademark of and BI SOLUTIONS PLUS is a service mark of Boehringer Ingelheim International GmbH, used under license.