Accessing Patient Support
The BI Solutions PlusTM patient support program is designed to help you throughout your journey with CYLTEZO®
(adalimumab-adbm). Once enrolled, you’ll have access to one-on-one support with a Patient Navigator and if eligible, a $0 copay.*
BI Solutions Plus—a patient program designed just for you
When starting on CYLTEZO, you can easily enroll in BI Solutions Plus online or over the phone with the help of a dedicated Patient Navigator. The one-on-one support provided by a Patient Navigator is available throughout your treatment journey.
Watch Sarah’s experience with her doctor and BI Solutions Plus when starting on CYLTEZO.
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At Boehringer Ingelheim, we're not just focused on creating medications that improve lives. We’re committed to making healthcare more accessible and supportive by working closely with both patients and healthcare providers.
BI Solutions PlusTM is our patient support program designed with your needs in mind. Take a look at how our team can help provide support to new patient Sarah.
Sarah has been taking Humira® for several years to manage her rheumatoid arthritis. Because of a recent insurance decision, her prescription is changing to CYLTEZO® (adalimumab-adbm).
Humira has a well-established track record and her rheumatologist, Dr. Franklin, knows it well. But he also appreciates that there are now more choices for the management of RA than there have been in the past, and he reassures Sarah that, CYLTEZO is the first interchangeable* biosimilar for Humira, and she can expect it to work the same way.
Dr. Franklin’s office is happy to see BI Solutions Plus resembles other patient support programs that they already know. They found it easy to access and submit an enrollment form on her behalf.
After enrollment, some patients like Sarah, choose to receive additional personalized support. BI Solutions Plus can help with that, too! She can enroll online at CYLTEZO.com or over the phone by calling 1-833-CYLTEZO. This will connect her to a dedicated Patient Navigator who can help throughout her journey with CYLTEZO.
Dr. Franklin's office staff tells Sarah that, due to her commercial insurance, CYLTEZO has a Copay Program that she may be eligible for and would pay as little as $0 per fill. Soon after enrolling for the Copay Program, Sarah receives an email message from the CYLTEZO Copay Program and instructions on how to use her benefits.
In many ways, BI Solutions Plus is helping both patients and healthcare providers.
BI Solutions Plus has dedicated insurance specialists that can assist Dr. Franklin’s office with determining coverage and helping offices navigate the prior authorization process. While Sarah benefits from a Patient Navigator from BI Solutions Plus, who serves as her main point of contact for support.
Sarah’s Patient Navigator not only helped her learn about resources available through BI Solutions Plus, she also explained how CYLTEZO works and connected her to a Clinical Educator who provided self-injection education.
The 1-on-1 injection education sessions with BI Clinical Educators can be provided both in-person or virtually, depending on availability and patient preference.
Thanks to the injection routine Sarah developed with her Clinical Educator, she also feels confident handling her CYLTEZO Pen and staying on schedule. Of course, if she has any questions, she can call her Patient Navigator for help at any time.
Sarah is impressed with the support she’s getting from BI Solutions Plus. In addition to the guidance, she was able to request a travel cold case to store and protect CYLTEZO on the go, along with a sharps container that includes a prepaid return label. Once the sharps container is full, she can send it back for a replacement.
BI Solutions Plus is a dedicated source of access and comprehensive support for both patients and healthcare providers. BI Solutions Plus is here for you!
To learn more about CYLTEZO, including complete Instructions for Use, storage and handling requirements, and possible side effects, please see the Medication Guide and Instructions for Use available on this website.
*The FDA first approved CYLTEZO as an interchangeable biosimilar (50 mg/mL) to Humira on October 15, 2021. CYLTEZO (100 mg/mL) has not yet been designated as interchangeable. For more information on interchangeability for CYLTEZO, please talk to your doctor or refer to the FDA’s resource on biosimilars and interchangeability, the Purple Book: https://purplebooksearch.fda.gov.
BI Solutions Plus offers comprehensive assistance, making your needs a priority
Once your doctor prescribes CYLTEZO or Adalimumab-adbm or you are switched by your pharmacy, enroll in BI Solutions Plus to take advantage of these resources:
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Help understanding insurance coverage benefits for CYLTEZO and your eligibility for any saving options through the CYLTEZO Copay Program.
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The CYLTEZO Copay Program, offered through BI Solutions Plus, may help eligible patients with commercial insurance, including insurance exchanges, federal employee plans, or state employee plans, pay as little as $0* per fill.
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One-on-one support with a Patient Navigator—connect with someone that can help answer questions and assist you throughout your journey with CYLTEZO.
Please note: A Patient Navigator cannot provide medical advice. Speak to your doctor if you have medical questions.
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Educational sessions with our Patient & Community Clinical Educators. Gain confidence through personalized educational sessions we offer about:
Your condition: Signs, symptoms, and management tips
Taking CYLTEZO: Dosing and administration and side effects
CYLTEZO injections: Preparing for and what to expect with the option to use a practice device.
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Receive a sharps disposal container or insulated travel bag for your CYLTEZO if needed.
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Multilingual support through translation services in over 100 languages, including Spanish.
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Local support with information on connecting with support groups, community events, and patient organizations.
Enroll in BI Solutions Plus to see if you are eligible for a $0 copay*
Support with BI Solutions Plus is just a click away. If you prefer to sign up by phone, call 1-833-CYLTEZO
(1-833-295-8396) Monday-Friday from 8:00 AM to 8:00 PM ET.
*Terms and Conditions apply and may change without notice.
This important information also applies to Adalimumab-adbm injection for subcutaneous use.
CYLTEZO is a medicine called a tumor necrosis factor (TNF) blocker. CYLTEZO is used:
- To reduce the signs and symptoms of:
- moderate to severe rheumatoid arthritis (RA) in adults. CYLTEZO can be used alone, with methotrexate, or with certain other medicines.
- moderate to severe polyarticular juvenile idiopathic arthritis (JIA) in children 2 years and older. CYLTEZO can be used alone or with methotrexate.
- psoriatic arthritis (PsA) in adults. CYLTEZO can be used alone or with certain other medicines.
- ankylosing spondylitis (AS) in adults.
- moderate to severe hidradenitis suppurativa (HS) in adults.
- To treat moderate to severe Crohn’s disease (CD) in adults and children 6 years of age and older.
- To treat moderate to severe ulcerative colitis (UC) in adults. It is not known if adalimumab products are effective in people who stopped responding to or could not tolerate TNF-blocker medicines.
- To treat moderate to severe chronic (lasting a long time) plaque psoriasis (Ps) in adults who have the condition in many areas of their body and who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light alone or with pills).
- To treat non-infectious intermediate, posterior, and panuveitis in adults.
This important information also applies to Adalimumab-adbm injection for subcutaneous use.
What is the most important information I should know about CYLTEZO?
You should discuss the potential benefits and risks of CYLTEZO with your doctor. CYLTEZO is a TNF-blocker medicine that can lower the ability of your immune system to fight infections. You should not start taking CYLTEZO if you have any kind of infection unless your doctor says it is okay.
- Serious infections have happened in people taking adalimumab products. These serious infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some people have died from these infections. Your doctor should test you for TB before starting CYLTEZO and check you closely for signs and symptoms of TB during treatment with CYLTEZO, even if your TB test was negative. If your doctor feels you are at risk, you may be treated with medicine for TB.
- Cancer. For children and adults taking TNF blockers, including CYLTEZO, the chances of getting lymphoma or other cancers may increase. There have been cases of unusual cancers in children, teenagers, and young adults using TNF blockers. Some people have developed a rare type of cancer called hepatosplenic T-cell lymphoma. This type of cancer often results in death. If using TNF blockers, including CYLTEZO, your chances of getting two types of skin cancer (basal cell and squamous cell) may increase. These types are generally not life-threatening if treated; tell your doctor if you have a bump or open sore that doesn’t heal.
What should I tell my doctor BEFORE starting CYLTEZO?
Tell your doctor about all of your health conditions, including if you:
- Have an infection, are being treated for infection, or have symptoms of an infection.
- Get a lot of infections or have infections that keep coming back.
- Have diabetes.
- Have TB or have been in close contact with someone with TB, or were born in, lived in, or traveled where there is more risk for getting TB.
- Live or have lived in an area (such as the Ohio and Mississippi River valleys) where there is an increased risk for getting certain kinds of fungal infections, such as histoplasmosis, coccidioidomycosis, or blastomycosis. These infections may happen or become more severe if you use CYLTEZO. Ask your doctor if you are unsure whether you have lived in an area where these infections are common.
- Have or have had hepatitis B.
- Are scheduled for major surgery.
- Have or have had cancer.
- Have numbness or tingling or a nervous system disease such as multiple sclerosis or Guillain-Barré syndrome.
- Have or had heart failure.
- Have recently received or are scheduled to receive a vaccine. CYLTEZO patients may receive vaccines, except for live vaccines. Children should be brought up to date on all vaccines before starting CYLTEZO.
- Are allergic to rubber or latex.
- Are allergic to any CYLTEZO ingredients.
- Are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed.
- Have a baby and you were using CYLTEZO during your pregnancy. Tell your baby’s doctor before your baby receives any vaccines.
Also tell your doctor about all the medicines you take. You should not take CYLTEZO with ORENCIA® (abatacept), KINERET® (anakinra), REMICADE® (infliximab),
ENBREL® (etanercept), CIMZIA® (certolizumab pegol), or SIMPONI® (golimumab). Tell your doctor if you have ever used RITUXAN® (rituximab), IMURAN®
(azathioprine), or PURINETHOL® (mercaptopurine, 6-MP).
What should I watch for AFTER starting CYLTEZO?
CYLTEZO can cause serious side effects, including:
- Serious infections. These include TB and infections caused by viruses, fungi, or bacteria. Symptoms related to TB include a cough, low-grade fever, weight loss,
or loss of body fat and muscle. - Hepatitis B infection in carriers of the virus. Symptoms include muscle aches, feeling very tired, dark urine, skin or eyes that look yellow, little or no appetite,
vomiting, clay-colored bowel movements, fever, chills, stomach discomfort, and skin rash. - Allergic reactions. Symptoms of a serious allergic reaction include hives; trouble breathing; and swelling of your face, eyes, lips, or mouth.
- Nervous system problems. Signs and symptoms include numbness or tingling, problems with your vision, weakness in your arms or legs, and dizziness.
- Blood problems (decreased blood cells that help fight infections or stop bleeding). Symptoms include a fever that does not go away, bruising or bleeding very
easily, or looking very pale. - Heart failure (new or worsening). Symptoms include shortness of breath, swelling of your ankles or feet, and sudden weight gain.
- Immune reactions, including a lupus-like syndrome. Symptoms include chest discomfort or pain that does not go away, shortness of breath, joint pain, or rash on your cheeks or arms that gets worse in the sun.
- Liver problems. Symptoms include feeling very tired, skin or eyes that look yellow, poor appetite or vomiting, and pain on the right side of your stomach
(abdomen). These problems can lead to liver failure and death. - Psoriasis (new or worsening). Symptoms include red scaly patches or raised bumps that are filled with pus.
Call your doctor or get medical care right away if you develop any of the above symptoms.
The most common side effects of CYLTEZO include injection site reactions (pain, redness, rash, swelling, itching, or bruising), upper respiratory infections (sinus
infections), headaches, and rash. These are not all the possible side effects with CYLTEZO. Tell your doctor if you have any side effect that bothers you or that does
not go away.
Remember to tell your doctor right away if you have an infection or symptoms of an infection, including:
- Fever, sweats, or chills
- Muscle aches
- Cough
- Shortness of breath
- Blood in phlegm
- Warm, red, or painful skin or sores on your body
- Diarrhea or stomach pain
- Burning when you urinate
- Urinating more often than normal
- Feeling very tired
- Weight loss
These are not all the possible side effects of CYLTEZO. For more information, speak with your doctor or pharmacist.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
CL-CTZ-100017 SEPT 2023